Mertz Holdings

Companies

Akido Labs is a Y Combinator funded startup that is leveraging secure computing technology created out of USC’s Health System to build the first nationwide network public service data. We integrate thousands of siloed, non-standard, sensitive data sources from local healthcare organizations and government agencies across the country to power solutions to systemic public health problems.

Alpha Cognition Inc. (ACI) is engaged in neurological disease research and has developed programs in Alzheimer’s Disease and amyotrophic lateral sclerosis (ALS).

· Alpha-1062 is a patented new chemical entity that has shown efficacy in preclinical and recently completed human clinical trials. It is being developed as a new generation acetylcholine esterase inhibitor (AcEI) with minimal gastrointestinal side effects and new routes of administration. Alpha-1062 is differentiated from donepezil and rivastigmine in that it appears to also sensitize neuronal nicotinic receptors, most notably the alpha-7 subtype, which may have a positive effect on the disease. The drug is entering pivotal clinical trials later this year.

· Alpha-602 (Progranulin) is a natural protein that is expressed in several cell types in the Central Nervous System and in peripheral tissues. Alpha-602 regulates cell survival and certain inflammatory processes. The protein plays a major role in regulating lysosomal function and microglial responses. Its use in the treatment of ALS has been patented by ACI and is being investigated in preclinical models.

Duo Security’s hosted two-factor authentication service brings strong, scalable security to organizations of any size. Duo’s unique, high-availability architecture provides centralized management, self-service enrollment, and interactive secondary login through an intuitive web interface, eliminating the high costs, complexity, and confusion associated with traditional two-factor systems. Every day, over 500 organizations in 40+ countries around the world rely on Duo for their security. This investment is through ResonantVC.

 

Sold to Cisco Q3 2018 for $2.3Bn Cash

FTW Ventures is an early-stage Venture Fund for innovation to solve massive world challenges in our Food System. FTW looks to the future, where we will need to feed 10B people on the planet by 2050, with less impact on our environment, using fewer, precious resources, in an uncertain global climate situation, but with higher yields and better nutritional value.

With investments in biotechnology, hardware, software/SaaS and novel food, FTW invests across a variety of deep science and technology areas to systematically improve the productivity, efficiency, resilience and sustainability of our Food & Agriculture sectors.

Founded by serial tech entrepreneur and food industry veteran, Brian Frank, and supported by a legion of exceptional Mentors including top scientists, leading food companies executives, and even celebrity chefs, FTW invests both time and capital into making their portfolio companies highly successful. Select holdings include positions in Geltor (synthetic biology for collagen production), Plantible (high-value protein cultivation and extraction) and Spoiler Alert (SaaS for surplus food management).

GeoDigital International, strives to meet the unique needs of every client. They provide laser based solutions for field data acquisition, asset mapping and visual infrared inspection – providing turnkey solutions for the Electric Utility, Highway & Road, Railway, Pipeline, Telecommunications, Fire Mapping and Utility Vegetation Management industries.

Green & Grow Inc. (GGI) is dedicated to developing and commercializing naturally derived compounds with new methods of action.

Trials to date show that GGI has successfully refined its Agriplier™ Technology for integration into multiple seed treatment processes and for liquid application as well as a soil amendment. Agriplier products are easy to apply, water soluble, and have a long shelf life. In addition, these fertilizers are not subject to the potential performance uncertainty inherent in the use of live micro-organisms and can be applied simultaneously with standard fertilizers, nutrients or crop protection products. GGI offers products that are USDA Certified as 100% Biobased and suited for organic farming.

Conduct, Compliance, and Policy: Automated

LitLingo evaluates communications with AI to identify relevant language, assist users in real-time and proactively reduce risk.

Neurodyn Inc. is a Canadian biotechnology company utilizing a portfolio approach to develop bioactives for the early treatment of neurological disease.

Neurodyn also houses a proprietary suite of animal models which are highly predictive, environmentally-based, and can replicate multiple aspects of human neurological disease states.

PhotoDynamic Inc. is disrupting the dental industry with their platform anti-biofilm technology and creating a new standard of at home oral health care.

Using botanical-based science and light to disrupt and destroy plaque in only 1 minute. PhotoDynamic has shown clinically that they can prevent bacterial colonization and build-up of plaque and tartar before it causes oral health problems, and potentially leads to serious chronic disease states. Prevention is key.

Plantible Foods is a B2B food technology company with the goal to develop the most functional and applicable plant-based protein in the world using scalable and sustainable aqua-farming and extraction technologies.

Resonant Venture Partners is an emerging venture capital firm based in Ann Arbor, Michigan. Founded in 2010, Resonant makes seed stage investments in companies developing cloud infrastructure, software and services. Entrepreneurs in their own right, the managing directors partner with portfolio companies through challenging product, market and operational issues at the earliest phases. At the same time, Resonant maintains a top tier back office, a disciplined approach to venture investing and a high level of service to their limited partners.

Robinhood Markets, Inc. is an American financial services company headquartered in Menlo Park, California. The company offers a mobile app and website that offer people the ability to invest in stocks, ETFs, and options through Robinhood Financial and crypto trading through Robinhood Crypto. Robinhood operates a website and mobile apps for iPhone, Apple Watch, and Android. The company has no storefront branches and operates entirely online without fees.

Space Exploration Technologies Corp. is an American aerospace manufacturer and space transportation services company headquartered in Hawthorne, California. SpaceX was founded in 2002 by Elon Musk with the goal of reducing space transportation costs to enable the colonization of Mars.

Triumvira Immunologics, Inc. (“Triumvira”) is an immunotherapy company co-founded in 2015 by Dr. Jonathan Bramson at McMaster University and Bloom Burton & Co., with the vision of developing novel T cell therapies that are safer and more efficacious than current cancer treatments, including chimeric antigen receptor (CAR) and engineered T cell receptor (TCR) therapies. The company’s proprietary T cell Antigen Coupler (TAC) technology recruits the entire natural T cell receptor and is independent of the major histocompatibility complex (MHC), allowing for the development of better therapies for a broader range of patients with solid or liquid malignancies and also with diseases other than cancer.

Triumvira’s lead therapeutic candidate, CD19-TAC01, is a CD19-directed T cell product for the treatment of B cell malignancies and is anticipated to enter Phase I clinical trials in early 2019 in patients with diffuse large B cell lymphoma (DLBCL). The company is also developing a series of products for solid tumors.

Triumvira is led by Dr. Paul Lammers, CEO & President, and an experienced management team with operational, clinic and product development expertise. Spanning the United States and Canada, headquarters are in Austin, Texas and research facilities are in Hamilton, Ontario.


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